Journal Articles
Serrano, J.; Smith, K.R.; Crouch, A.L.; Sharma, V. et al., "High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice" Microbiome 9 (2021) 11-11-11-11
Chen, D.; Zhu, X.; Ilavsky, J.; Whitmer, T. et al., "Polyphenols Weaken Pea Protein Gel by Formation of Large Aggregates with Diminished Noncovalent Interactions." Biomacromolecules 22 2 (2021) 1001-1014-1001-1014
Vasas, M.; Tang, F.; Chatzakis, E., "Application of NMR and Chemometrics for the Profiling and Classification of Ale and Lager American Craft Beer" Foods 10 (2021) 807-807-807-807
Tang, F.; Green, H.; Wang, S.; Chatzakis, E., "Analysis and Authentication of Avocado Oil Using High Resolution NMR Spectroscopy" Molecules 26 (2021) 310-310-310-310
Macknera, L.; Hatzakis, E.; Allen, J.; Davies, R. et al., "Fecal microbiota and metabolites are distinct in a pilot study of pediatric Crohn’s disease patients with higher levels of perceived stress." Psychoneuroendocrinology 111 (2020) 104469.-104469.-104469.-104469.
Wang, T.; Liu, Q.; Wang, M.; Zhou, J. et al., "Quantitative Measurement of a Chiral Drug in a Complex Matrix: a J-compensated HSQC (QHSQC) NMR Method." Analytical Chemistry 92 (2020) 3636-3642-3636-3642
Zhang, L.; Rimal, B.; Nichols, R.; Tian, Y. et al., "Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice" Toxicology 431 (2020) 152365-152365-152365-152365
Crawford, L.; Janovick, J.; Carrasquilla-Garcia, N.; Hatzakis, E. et al., "Comparison of DNA analysis, targeted metabolite profiling, and non-targeted NMR fingerprinting for differentiating cultivars of processed olives" Food Control (2020) 107264-107264-107264-107264
Tang, F.; Hatzakis, E., "NMR-based analysis of pomegranate juice using untargeted metabolomics coupled with nested and quantitative approaches" Analytical Chemistry 92 (2020) 11177-11185-11177-11185
Williamson, K.; Hatzakis, E., "Evaluating the effect of roasting on coffee lipids using a hybrid targeted-untargeted NMR approach in combination with MRI" FOOD CHEMISTRY 299 (2019) 125039-125039-125039-125039
Buiten, C.; Yennawar, N.; Pacheco, C.; Hatzakis, E. et al., "Physicochemical interactions with (−)-epigallocatechin-3-gallate drive structural modification of celiac-associated peptide α2-gliadin (57–89) at physiological conditions" Food & Function 10 (2019) 2997-3007-2997-3007
Hatzakis, E.; Mazzola, E.; Shegoc, R.; Ziegler, G. et al., "Perseorangin: A Natural Pigment from Avocado (Persea americana) Seed" Food Chemistry 293 (2019) 15-22-15-22
Hatzakis, E., "Nuclear Magnetic Resonance (NMR) spectroscopy in food science: A comprehensive review" COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY 18 (2019) 189-220-189-220
Williamson, K.; Hatzakis, E., "NMR analysis of roasted coffee lipids and development of a spent ground coffee application for the production of bioplastic precursors" Food Research International 119 (2019) 683-692-683-692
Tang, F.; Vasas, M.; Hatzakis, E.; Spyros, A., "Magnetic resonance applications in food analysis." Annual Reports on NMR Spectroscopy 98 (2019) 239-306-239-306
Dong, M.; Xu, X.; Huang, Q.; Lei, H. et al., "Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats." Chemical Research in Toxicology 32 (2019) 2320-2328-2320-2328
Cai, J.; Zhang, J.; Tian, Y.; Zhang, L. et al., "Orthogonal Comparison of GC-MS and 1 H NMR Spectroscopy for Short Chain Fatty Acid Quantitation" Analytical Chemistry 89 15 (2017) 7900-7906-7900-7906
Lin, Y-C.; Hatzakis, E.; McCarthy, S.M.; Reichl, K.D. et al., "P–N Cooperative Borane Activation and Catalytic Hydroboration by a Distorted Phosphorous Triamide Platform" Journal of the American Chemical Society 139 16 (2017) 6008-6016-6008-6016
Williamson, K.W.; Hatzakis, E.H., "NMR Spectroscopy as a robust tool for the rapid evaluation of the lipid profile of fish oil supplements" Jove-Journal of Visualized Experiments 123 (2017) e55547-e55547-e55547-e55547
Dais, P.; Plessel, R.; Williamson, K.; Hatzakis, E.H., "Complete 1H and 13C NMR assignment and 31P NMR determination of pentacyclic triterpenic acids" Analytical Methods 9 (2017) 949-957-949-957
Zhang, L.; Xie, C.; Nichols, R.; Chan, S. et al., "Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism." mSystems 1 (2016) 1-17-1-17
Zhang, L.; Hatzakis, E.; Patterson, A., "NMR-Based Metabolomics and Its Application in Drug Metabolism and Cancer Research" Current Pharmacology Reports 2 (2016)
Cai, J.; Zhang, L.; Jones, R.; Correll, J.; Hatzakis, E.; Smith, P.; Gonzalez, F.; Patterson, A, "The Anti-Oxidant Drug Tempol Promotes a State of Anti-Obesity Through Functional Metabolic Changes in the Gut Microbiota" Journal of Proteome Research 15 (2016) 563−571-563−571
Soo, V.W.C.; McAnulty, M.J.; Tripathi, A.; Zhu, F. et al., "Reversing methanogenesis to capture methane for liquid biofuel precursors" Microbial Cell Factories 15 1 (2016)
Dey, K.; Pong, F.; Breffke, J.; Pavlick, R.; Hatzakis, E.; Pacheco, C.; Sen, A., "Dynamic Coupling at the Ångström Scale" Angewandte Chemie 55 (2016) 1113-1117-1113-1117
Zhang, L.; Hatzakis, E.; Nichols, R.; Correll, J.; Smith, P.; Perdew, G.; Patterson, A. Metabolic responses of mice to dietary TCDF revealed by a combination of global and targeted analysis, "Metabolic responses of mice to dietary TCDF revealed by a combination of global and targeted analysis" Environmental Science and Technology 49 (2015) 8067–8077-8067–8077
Dais, P.; Misiak, M.; and Hatzakis, E., "Analysis of marine dietary supplement using NMR spectroscopy" Analytical Methods 7 (2015) 5226-5238-5226-5238
Zhang, L.; Correll, R.; Tanaka, N.; Murray, I.; Smith, P.; Hao, R.; Albert, I.; Hatzakis, E.; Gonzalez, F.; Perdew, G.;. Patterson, A., "Aryl Hydrocarbon Receptor Activation by Persistent Organic Pollutants Impacts Gut Microbiome-Host Metabolic Homeostasis." Environmental Health Perspectives 123 (2015) 679-688. Science Selections, p. A187-679-688. Science Selections, p. A187
Aumiller, W.M.; Davis, B.W.; Hatzakis, E.; Keating, C.D., "Interactions of macromolecular crowding agents and cosolutes with small-molecule substrates: Effect on horseradish peroxidase activity with two different substrates" Journal of Physical Chemistry B 118 36 (2014) 10624-10632-10624-10632
Mathé, E.A.; Patterson, A.D.; Haznadar, M.; Manna, S.K. et al., "Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer" Cancer Research 74 12 (2014) 3259-3270-3259-3270
Agrawal P.; Hatzakis, E; Guo, K.; Yang, D., "Solution Structure of the Biologically Relevant G- Quadruplex Element in the Human VEGF Promoter." Nucleic Acids Research 41 (2013) 10584–10592-10584–10592
Dais, P.; Hatzakis, E, "Quality assessment and authentication of virgin olive oil by NMR spectroscopy. A critical review." Analytica Chimica Acta 765 (2013) 1-27-1-27
Orfanakis, A.; Hatzakis, E.; Pergantis, S.; Rizos, A.; Dais P., "Structure elucidation of Polyglycerol Polyricinolate (PGPR) by light scattering, LC-MS and NMR spectroscopy." Journal of the American Oil Chemists' Society 90 (2013) 39-51-39-51
Chen, Y.; Agrawal, P.; Brown, R.V.; Hatzakis, E. et al., "The major G-quadruplex formed in the human platelet-derived growth factor receptor β promoter adopts a novel broken-strand structure in K+ solution" Journal of the American Chemical Society 134 32 (2012) 13220-13223-13220-13223
Hatzakis, E.; Agiomirgianaki, A.; Kostidis, S.; Dais, P., "High-resolution NMR spectroscopy: An alternative fast tool for qualitative and quantitative analysis of diacylglycerol (DAG) oil." Journal of the American Oil Chemists' Society 88 (2011) 1695–1708-1695–1708
Mathad, R.; Hatzakis, E.; Dai, J.; Yang, D., "c-Myc promoter G-quadruplex formed at the 5’-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability." Nucleic Acids Research 39 (2011) 9023-9033-9023-9033
Hatzakis, E; Okamoto, K.; Yang, D., "Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop-isomers formed in the Nuclease Hypersensitive Element in the human c-Myc promoter-Effect of loops and flanking segments on the stability of parallel-stranded intramolecular G-quadruplexes." Biochemistry 49 (2010) 9152–9160-9152–9160
Hatzakis, E.; Dagounakis, G.; Agiomirgianaki, A.; Dais, P., "A Facile NMR Method for the Quantification of Total Free and Esterified Sterols in Virgin Olive Oil." Food Chemistry 122 (2010) 346-352-346-352
Dai J.; Hatzakis, E.; Hurley, L.; Yang, D., "The Folding Structures and the Dynamic Character of the Major I -motif Formed in the Human c-Myc Promoter- Insights into sequence redundancy and I-motif stability." Plos One 5 (2010) e11647-e11647
Hatzakis, E.; Agiomyrgianaki, A.; Dais, P., "Detection and quantification of free glycerol in virgin olive oil by 31P NMR Spectroscopy" Journal of the American Oil Chemists' Society 87 (2010)
Hatzakis, E.; Koidis, A; Boskou, D.; Dais, P., "Determination of phospholipids in olive oil by 31P NMR Spectroscopy" Journal of Agricultural and Food Chemistry 56 (2008) 6232-6240-6232-6240
Hatzakis, E.; Dais, P., "Determination of Water Content in Olive oil by 31P NMR Spectroscopy." Journal of Agricultural and Food Chemistry 56 (2008) 1866-1872-1866-1872
Hatzakis, E.; Archavlis, L.; Dais, P., "Determination of Glycerol in Wines Using 31P-NMR Spectroscopy." Journal of the American Oil Chemists' Society 84 (2007) 615-619-615-619
Hatzakis, E.; Opsenica, I.; Solaja, B.; Stratakis, M., "Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridol and dihydroascaridole." Arkivoc 8 (2007) 124-135-124-135
Dais, P.; Spyros, A.; Christoforidou, S.; Hatzakis, E.; Fragaki, G.; Agiomirgianaki, A.; Salivaras, E.; Siragakis, G.; Daskalaki, D.; Margari, M.; Brenes, M., "Comparison of Analytical Methodologies Based on 1H and 31P NMR Spectroscopy with Conventional Methods of Analysis for the Determination of Some Olive Oil Constituents" Journal of Agricultural and Food Chemistry 55 (2007) 577-584-577-584
Chapters
"Analysis of Bioactive Microconstituents in Olives, Olive Oil, and Olive Leaves by NMR Spectroscopy: An Overview of the Last Decade" In Olive Oil and Olive Oil Bioactive Constituents. Edited by Boskou D. 2015.
Patents
Single-use coffee cup polyurethane liner from spent coffee ground oil. Filed Jan 2021
Biobased, compostable water impermeable coating for carboard food packaging applications. Filed Jan 2020
G. Ziegler, J. Lambert, R. Shegog, E. Hatzakis, D. Dabas. Compounds and Compositions and Methods for Coloring Edible Materials. Filed Nov 2016
Presentations
"NMR applications in Food Science." In Rising stars in food science. 2021.
"NMR applications in Food Science." In Department of Food Science & Technology, University of California, Davis. 2021.
"NMR spectroscopy in food analysis and quality control." In International Webinar on Food Science & Food Chemistry. 2021.
"NMR-based metabolomics in food science." In The National Dairy Research Institute (NDRI). 2021.
"Advanced NMR approaches as a tool for food quality control." In 6th Food Ingredient Asia Conference (FiAC) on Food Science, Nutrition and Health. 2020.
"NMR in food analysis." In 6th International Conference on Food Chemistry & Technology, FCT-2020. 2020.
"Linking genomics and metabolomics for nutrient-driven germplasm improvement in apples.." In Ohio State University Plant Sciences Symposium. 2020.
"Linking genomics and metabolomics for nutrient-driven germplasm improvement in apples." In Ohio Valley Institute of Food Technologists Poster Competition. 2020.
"Linking genomics and metabolomics for nutrient-driven germplasm improvement in apples." In The Ohio State University Hayes Graduate Research Forum. 2020.
"NMR applications in Food Science." In Departmental Seminar Food Science and Technology. 2020.
"Advanced NMR approaches as a tool for food quality control." In 6th International Conference on Food Chemistry & Technology. 2020.
"Advanced NMR approaches as a tool for food quality control." In 6th Food Ingredient Asia Conference (FiAC) on Food Science, Nutrition and Health. 2020.
"Linking genomics and metabolomics for nutrition-driven germplasm improvement of apples." In 3rd Annual Ohio Mass Spectrometry and Metabolomic Symposium. 2019.
"Linking genomics and metabolomics for nutrition-driven germplasm improvement of apples.." In Horticulture and Crop Science Graduate Research Symposium,. 2019.
"NMR Applications in Food Science and Nutrition." In IFT. 2019.
"Improving food quality and agricultural sustainability through NMR-based approaches." In Gateway NMR conference. 2019.
"Differentiating the cultivar of processed olives using DNA, fatty acid profile and NMR fingerprinting methods." In 257th National Meeting of the American-Chemical-Society (ACS). 2019.
"Producing value-added products from food waste: Bioplastic Precursors from Spent Coffee Grounds and a Natural Colorant from Avocado Seeds." In The International Union of Food Science and Technology (IUFoST) 19th World Food Science and Technology Congress. 2018.
"Edibolomics Food quality-Value-added products." In IFT. 2018.
"Integrating NMR- and MS-based Metabolomics." In 66th ASMS Conference on Mass Spectrometry and Allied Topics. 2018.
"Monitoring Food Quality and Producing Value-added Products from Food Waste using NMR-based Approaches." In 2nd Annual Ohio Mass Spectrometry and Metabolomics Symposium. 2018.
"NMR Detective, a Magnetic Tool for Identifying the Various Classes of Food Components." In University of Maryland, Department of Chemistry. 2017.
"Revealing secrets with a magnet: A robust approach to promote health and consumer safety." In U.S. Food and Drug Administration (FDA), Center for Food Safety and Applied Nutrition (CFSAN). 2017.
"NMR spectroscopy as a versatile tool in food science and metabolomics." In Flavor Research and Education Center (FREC), OSU. 2017.
"Analysis and Assessment of the Lipid Fraction of Coffea arabica Beans - an NMR Approach." In American Society for Horticultural Science (ASHS). 2017.
"Applications of NMR spectroscopy in food analysis and in health and disease." In Mid Atlantic Regional Meeting ACS. 2017.
"Carbon-13 detected NMR for the Quantification of EPA and DHA in Fish Oil Supplements." In Experimental Nuclear Magnetic Resonance Conference (ENC). 2017.
"Improving food quality and human health using NMR spectroscopy and metabolomics." In External Advisory Board Industry, OSU, FST. 2017.
"Improving food quality and human health using NMR spectroscopy and metabolomics." In External Advisory Board Industry, OSU. 2017.
"NMR spectroscopy as a versatile tool in food science and metabolomics." In Flavor Research and Education Center (FREC), OSU. 2017.
"NMR spectroscopy in food science and metabolomics." In OSU Interdisciplinary PhD Program in Nutrition. 2016.
"NMR spectroscopy as a versatile tool in food science and metabolomics." In FALL 2016 OSU NUTRITION PROGRAM SEMINAR SERIES. 2016.
Technical Reports
Jones, J.; Chatzakis, E., "Food Processing: Opportunities and Challenges" 2021.
