Dr. Christopher Simons

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Profile

Associate Professor

simons.103@osu.edu

http://u.osu.edu/simonslab/

614-688-1489

Office:

315 Parker Food Science and Technology Building

Professional Information

Interests & Expertise:

sensory science, chemical senses, food intake, consumer behavior

Biography:

Dr. Christopher Simons earned his undergraduate degree in Biology from the University of Oregon, his M.S. degree in Physiology from Portland State University in Portland, OR, and his Ph.D. in Sensory Science from the University of California, Davis. Subsequently, Chris completed post-doctoral fellowships in the Laboratoire de Neurobiologie Sensorielle [Sensory Neurobiology Laboratory] at the Ecole Pratiques des Hautes Etudes in Massy, France and the Unités de Formation et Recherche de la Odontologie [Dental School] at the Universite Paris 7. From 2004 through 2012 Chris led the Sensory Research function at Givaudan Flavors Corp. and joined the faculty in the Department of Food Science and Technology at the Ohio State University in 2013. Dr. Simons’s research interests use a multidisciplinary approach to understand the perception of foods and how they are processed to influence reward and, ultimately, behavior. One outcome of this research is to identify the neural and physiological correlates associated with perception, liking, and food choice using a variety of methodologies including human sensory testing or psychophysics, electrophysiology, and behavioral measurements. Another outcome is to leverage the knowledge gained from these types of investigations to develop new methodologies that assist in the creation of better foods. In 2017, Chris was awarded the Barry Jacobs Memorial Award for Research in the Psychophysics of Human Taste and Smell by the Association for Chemoreception Sciences and in 2018 he received the Educator Award from the North American Colleges and Teachers of Agriculture association.

Area of Expertise: Sensory Evaluation and Psychophysics. Methodology Development. Neural and physiological underpinnings of sensation, reward and consumer decision. Functional and cognitive benefits of flavors and food ingredients.

Works

Journal Articles

Cotter, M.T.; Peterson, D.G.; Simons, C.T., "The impact of multi-session testing on panelist engagement measured by the engagement Questionnaire (EQ)" Food Quality and Preference 96 (2022)

Cong, W.; Schwartz, E.; Tello, E.; Simons, C.T. et al., "Identification of non-volatile compounds that negatively impact whole wheat bread flavor liking." Food Chem 364 (2021) 130362-130362

Hannum, M.E.; Fryer, J.A.; Simons, C.T., "Non-food odors and the duality of smell: Impact of odorant delivery pathway and labeling convention on olfactory perception." Physiol Behav 238 (2021) 113480-113480

Hannum, M.E.; Forzley, S.; Popper, R.; Simons, C.T., "Application of the Engagement Questionnaire (EQ) to compare methodological differences in sensory and consumer testing" Food Research International 140 (2021)

Bogdanov, V.; Reinhard, J.; McGlone, F.; Haehner, A. et al., "Oral Somatosensory Sensitivity in Patients With Taste Disturbance" Laryngoscope (2021)

Braun, A.; Simons, C.; Kilbarger, J.; Hill, E.B. et al., "Sensory perceptions of survivors of cancer and their caregivers upon blinded evaluation of produce from two different sources" Supportive Care in Cancer (2021)

Albiol Tapia, M.; Baik, H.Y.; Simons, C.T.; Lee, S.Y., "Context effect of environmental setting and product information in acceptability testing of tea and cola: A study comparing sensory engagement in a traditional sensory booth and a study commons" Journal of Food Science (2021)

Miles, B.L.; Ang, S.L.; Simons, C.T., "Development of a “pure-tactile” assessment of edge discrimination in the hands and oral cavity" Physiology and Behavior 224 (2020)

Hannum, M.E.; Forzley, S.; Popper, R.; Simons, C.T., "Further validation of the engagement questionnaire (EQ): Do immersive technologies actually increase consumer engagement during wine evaluations?" Food Quality and Preference 85 (2020)

Berry, D.N.; Simons, C.T., "Do Caucasian American and South Asian Indian cultural groups differ in sensitivity to capsaicin? A study designed to control for chili pepper affinity" Journal of Food Science 85 9 (2020) 2896-2901-2896-2901

Berry, D.N.; Simons, C.T., "Assessing regional sensitivity and desensitization to capsaicin among oral cavity mucosae" Chemical Senses 45 6 (2020) 457-466-457-466

Hannum, M.E.; Simons, C.T., "Development of the engagement questionnaire (EQ): A tool to measure panelist engagement during sensory and consumer evaluations" Food Quality and Preference 81 (2020)

Guttman, G.A.; Soldavini, A.; Simons, C.T., "Ethanol thresholds in water and beers" JOURNAL OF SENSORY STUDIES 35 1 (2020) 312544-312544-312544-312544

Paravisini, L.; Soldavini, A.; Peterson, J.; Simons, C.T. et al., "Impact of bitter tastant sub-qualities on retronasal coffee aroma perception" PLoS ONE 14 10 (2019)

Hannum, M.; Forzley, S.; Popper, R.; Simons, C.T., "Does environment matter? Assessments of wine in traditional booths compared to an immersive and actual wine bar" FOOD QUALITY AND PREFERENCE 76 (2019) 100-108-100-108

Simons, C.T.; Klein, A.H.; Carstens, E., "Chemogenic Subqualities of Mouthfeel." CHEMICAL SENSES (2019)

Liu, R.; Hannum, M.; Simons, C.T., "Using immersive technologies to explore the effects of congruent and incongruent contextual cues on context recall, product evaluation time, and preference and liking during consumer hedonic testing" Food Research International 117 (2019) 19-29-19-29

Simons, C.T., "Left out in the cold: Serving wines chilled." Temperature (Austin) 6 1 (2019) 1-3-1-3

Miles, B.L.; Van Simaeys, K.; Whitecotton, M.; Simons, C.T., "Comparative tactile sensitivity of the fingertip and apical tongue using complex and pure tactile tasks" Physiology and Behavior 194 (2018) 515-521-515-521

Hannum, M.; Stegman, M.A.; Fryer, J.A.; Simons, C.T., "Different olfactory percepts evoked by orthonasal and retronasal odorant delivery" Chemical Senses 43 7 (2018) 515-521-515-521

Roe, B.F.; Phinney, D.M.; Simons, C.T.; Badiger, A.S. et al., "Discard Intentions Lower for Milk Presented in Containers without Date Labels" Food Quality and Preference 66 (2018) 13-18-13-18

Simons, C.T.; Hagan, L.L.; Johnson, P.T.; Obodai, M. et al., "Sensory Attributes of Three Edible Tropical Mushrooms and Their Use in Formulating Food Products for Children 2 -5 Years Old" International Journal of Nutrition and Food Sciences 7 3 (2018) 100-109-100-109

Pierce, A.M.; Simons, C.T., "Olfactory adaptation is dependent on route of delivery" CHEMICAL SENSES 43 3 (2018) 197-203-197-203

Vasquez-Orejarena, E.; Simons, C.T.; Litchfield, J.H.; Alvarez, V.B., "Functional Properties of Oat-β-glucan in a High Protein Formulation Beverage" JOURNAL OF FOOD SCIENCE 83 5 (2018) 1360-1365-1360-1365

Simons, C.T.; Hooker, N.; Parasidis, E., ""Natural" Food Claims: Industry Practices, Consumer Expectations, and Class Action Lawsuits" Food and Drug Law Journal 73 (2018) 319-337-319-337

Linne, B.; Simons, C.T., "Quantification of oral roughness perception and comparison with mechanism of astringency perception." Chemical Senses 42 7 (2017) 425-435-425-435

Bangcuyo, R.G.; Simons, C.T., "Lingual tactile sensitivity: effect of age group, sex, and fungiform papillae density." EXPERIMENTAL BRAIN RESEARCH 235 9 (2017) 2679-2688-2679-2688

Cotten, B.M.; Diamond, S.; Banh, T.; Hsiao, Y-H. et al., "Raspberry ketone fails to reduce adiposity beyond decreasing food intake in mice fed a high-fat diet" Food and Function 8 (2017) 1512-1518-1512-1518

Hathaway, D.; Simons, C.T., "The impact of multiple immersion levels on data quality and panelist engagement for the evaluation of cookies under a preparation-based scenario" Food Quality and Preference 57 (2017) 114-125-114-125

Liu, R.; Hooker, N.H.; Parasidis, E.; Simons, C.T., "A natural experiment: using immersive technologies to study the impact of “all-natural” labeling on perceived food quality and liking." Journal of Food Science: Sensory and Food Quality (Fast Track) 82 3 (2017) 825-833-825-833

Tsourides, K.; Shariat, S.; Nejati, H.; Gandhi, T. et al., "Neural correlates of the food/non-food visual distinction" Biological Psychology 115 (2016) 35-42-35-42

Weiss, W.P.; Simons, C.T.; Ekmay, R.D., "Effects of feeding diets based on transgenic soybean meal and soybean hulls to dairy cows on production measures and sensory quality of milk" Journal of Dairy Science 98 12 (2015) 8986-8993-8986-8993

Parasidis, E.; Hooker, N.; Simons, C., "Addressing Consumer Confusion Surrounding “Natural” Food Claims" American Journal of Law and Medicine 41 2-3 (2015) 357-373-357-373

Simons, C.T., "An Introduction to this Special Issue: Animal Models of Human Chemosensory Perception and Behavior" Chemosensory Perception 8 2 (2015) 45-45

Bangcuyo, R.G.; Smith, K.J.; Zumach, J.L.; Pierce, A.M. et al., "The use of immersive technologies to improve consumer testing: the role of ecological validity, context and engagement in evaluating coffee" Food Quality and Preference 41 (2015) 84-95-84-95

Song, H.S.; Jin, H.J.; Ahn, S.R.; Kim, D. et al., "Bioelectronic Tongue Using Heterodimeric Human Taste Receptor for the Discrimination of Sweeteners with Human-Like Performance" ACS Nano 8 10 (2014) 9781-9789-9781-9789

Boucher, Y.; Simons, C.T.; Ioda Carstens, M.; Carstens, E., "Effects of gustatory nerve transection and/or ovariectomy on oral capsaicin avoidance in rats" Pain 155 (2014) 814-820-814-820

Liu, E.; Lewis, K.; Al-Saffar, H.; Krall, C.M. et al., "Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide- and Escherichia coli-induced systemic inflammation" AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 302 12 (2012) R1372-R1383-R1372-R1383

Klein, A.H.; Carstens, M.I.; McCluskey, T.S.; Blancher, G. et al., "Novel Menthol-Derived Cooling Compounds Activate Primary and Second-Order Trigeminal Sensory Neurons and Modulate Lingual Thermosensitivity" CHEMICAL SENSES 36 7 (2011) 649-658-649-658

Klein, A.H.; Sawyer, C.M.; Zanotto, K.L.; Ivanov, M.A. et al., "A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats" JOURNAL OF NEUROPHYSIOLOGY 105 4 (2011) 1701-1710-1701-1710

Shankar, M.; Simons, C.; Levitan, C.; Shiv, B. et al., "An expectations-based approach to explaining the crossmodal influence of color on orthonasal olfactory identification: assessing the influence of temporal and spatial factors" JOURNAL OF SENSORY STUDIES 25 6 (2010) 791-803-791-803

Shankar, M.; Simons, C.; Shiv, B.; McClure, S. et al., "An Expectation-Based Approach to Explaining the Crossmodal Influence of Color on Orthonasal Odor Identification: The Influence of Expertise" CHEMOSENSORY PERCEPTION 3 3-4 (2010) 167-173-167-173

Shankar, M.; Simons, C.; Shiv, B.; McClure, S. et al., "An expectations-based approach to explaining the cross-modal influence of color on orthonasal olfactory identification: The influence of the degree of discrepancy" ATTENTION PERCEPTION & PSYCHOPHYSICS 72 7 (2010) 1981-1993-1981-1993

Fushan, A.A.; Simons, C.T.; Slack, J.P.; Drayna, D., "Association between Common Variation in Genes Encoding Sweet Taste Signaling Components and Human Sucrose Perception" CHEMICAL SENSES 35 7 (2010) 579-592-579-592

Slack, J.; Brockhoff, A.; Batram, C.; Menzel, S. et al., "Modulation of Bitter Taste Perception by a Small Molecule hTAS2R Antagonist" CURRENT BIOLOGY 20 12 (2010) 1104-1109-1104-1109

Albin, K.C.; Simons, C.T., "Psychophysical Evaluation of a Sanshool Derivative (Alkylamide) and the Elucidation of Mechanisms Subserving Tingle" PLOS ONE 5 3 (2010) e9520-e9520-e9520-e9520

Carstens, E.E.; Mirela, I.; Simons, C.T.; Jinks, S.L., "Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats" NEUROREPORT 21 4 (2010) 303-308-303-308

Fushan, A.A.; Simons, C.T.; Slack, J.P.; Manichaikul, A. et al., "Allelic Polymorphism within the TAS1R3 Promoter Is Associated with Human Taste Sensitivity to Sucrose" CURRENT BIOLOGY 19 15 (2009) 1288-1293-1288-1293

Sawyer, C.M.; Carstens, M.I.; Simons, C.T.; Slack, J. et al., "Activation of Lumbar Spinal Wide-Dynamic Range Neurons by a Sanshool Derivative" JOURNAL OF NEUROPHYSIOLOGY 101 4 (2009) 1742-1748-1742-1748

Carstens, E.; Albin, K.C.; Simons, C.T.; Carstens, M.I., "Time course of self-desensitization of oral irritation by nicotine and capsaicin" CHEMICAL SENSES 32 9 (2007) 811-816-811-816

Simons, C.T.; Boucher, Y.; Carstens, M.J.I.; Carstens, E., "Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract" JOURNAL OF NEUROPHYSIOLOGY 96 4 (2006) 1877-1886-1877-1886

Simons, C.T.; Cuellar, J.M.; Moore, J.A.; Pinkerton, K.E. et al., "Nicotinic receptor involvement in antinociception induced by exposure to cigarette smoke" NEUROSCIENCE LETTERS 389 2 (2005) 71-76-71-76

Anderson, K.L.; Pinkerton, K.E.; Uyeminami, D.; Simons, C.T. et al., "Antinociception induced by chronic exposure of rats to cigarette smoke" NEUROSCIENCE LETTERS 366 1 (2004) 86-91-86-91

Simons, C.T.; Sudo, S.; Sudo, M.; Carstens, E., "Mustard oil has differential effects on the response of trigeminal caudalis neurons to heat and acidity" PAIN 110 1-2 (2004) 64-71-64-71

Nojima, H.; Cuellar, J.M.; Simons, C.T.; Carstens, M.L. et al., "Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus" NEUROSCIENCE LETTERS 361 1-3 (2004) 79-82-79-82

Simons, C.T.; Sudo, S.; Sudo, M.; Carstens, E., "Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation" BRAIN RESEARCH 991 1-2 (2003) 249-253-249-253

Nojima, H.; Simons, C.T.; Cuellar, J.M.; Carstens, M.I. et al., "Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin" JOURNAL OF NEUROSCIENCE 23 34 (2003) 10784-10790-10784-10790

Romanovsky, A.A.; Sugimoto, N.; Simons, C.T.; Hunter, W.S., "The organum vasculosum laminae terminalis in immune-to-brain febrigenic signaling: a reappraisal of lesion experiments" AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 285 2 (2003) R420-R428-R420-R428

Simons, C.T.; Carstens, M.I.; Carstens, E., "Oral irritation by mustard oil: Self-desensitization and cross-desensitization with capsaicin" CHEMICAL SENSES 28 6 (2003) 459-465-459-465

Simons, C.T.; Noble, A.C., "Challenges for the sensory sciences from the food and wine industries" NATURE REVIEWS NEUROSCIENCE 4 7 (2003) 599-605-599-605

Boucher, Y.; Simons, C.T.; Faurion, A.; Azerad, J. et al., "Trigeminal modulation of gustatory neurons in the nucleus of the solitary tract" BRAIN RESEARCH 973 2 (2003) 265-274-265-274

Sudo, S.; Sudo, M.; Simons, C.T.; Dessirier, J.M. et al., "Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride" BRAIN RESEARCH 969 1-2 (2003) 237-243-237-243

Cuellar, J.M.; Jinks, S.L.; Simons, C.T.; Carstens, E., "Deletion of the preprotachykinin A gene in mice does not reduce scratching behavior elicited by intradermal serotonin" NEUROSCIENCE LETTERS 339 1 (2003) 72-76-72-76

Simons, C.T.; Boucher, Y.; Carstens, M.I.; Carstens, E., "Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis" CHEMICAL SENSES 28 3 (2003) 253-259-253-259

Simons, C.T.; Boucher, Y.; Carstens, E., "Suppression of central taste transmission by oral capsaicin" JOURNAL OF NEUROSCIENCE 23 3 (2003) 978-985-978-985

Boucher, Y.; Simons, C.T.; Cuellar, J.M.; Jung, S.W. et al., "Activation of brain stem neurons by irritant chemical stimulation of the throat assessed by c-fos immunohistochemistry" EXPERIMENTAL BRAIN RESEARCH 148 2 (2003) 211-218-211-218

Sudo, S.; Sudo, M.; Simons, C.T.; Dessirier, J.M. et al., "Sensitization of trigeminal caudalis neuronal responses to intraoral acid and salt stimuli and desensitization by nicotine" PAIN 98 3 (2002) 277-286-277-286

Simons, C.T.; Gogineni, A.G.; Carstens, M.I.; Carstens, E., "Reduced aversion to oral capsaicin following neurotoxic destruction of superficial medullary neurons expressing NK-1 receptors" BRAIN RESEARCH 945 1 (2002) 139-143-139-143

Jinks, S.L.; Simons, C.T.; Dessirier, J.M.; Carstens, M.I. et al., "c-fos induction in rat superficial dorsal horn following cutaneous application of noxious chemical or mechanical stimuli" EXPERIMENTAL BRAIN RESEARCH 145 2 (2002) 261-269-261-269

Simons, C.T.; O'Mahony, M.; Carstens, E., "Taste suppression following lingual capsaicin pre-treatment in humans" CHEMICAL SENSES 27 4 (2002) 353-365-353-365

Carstens, E.; Anderson, K.A.; Simons, C.T.; Carstens, M.I. et al., "Analgesia induced by chronic nicotine infusion in rats - Differences by gender and pain test" PSYCHOPHARMACOLOGY 157 1 (2001) 40-45-40-45

Dessirier, J.M.; Simons, C.T.; O'Mahony, M.; Carstens, E., "The oral sensation of carbonated water: Cross-desensitization by capsaicin and potentiation by amiloride" CHEMICAL SENSES 26 6 (2001) 639-643-639-643

Simons, C.T.; Dessirier, J.M.; Jinks, S.L.; Carstens, E., "An animal model to assess aversion to intra-oral capsaicin: Increased threshold in mice lacking substance P" CHEMICAL SENSES 26 5 (2001) 491-497-491-497

Szekely, M.; Balasko, M.; Kulchitsky, V.A.; Simons, C.T. et al., "Multiple neural mechanisms of fever" AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL 85 1-3 (2000) 78-82-78-82

Ivanov, A.I.; Kulchitsky, V.A.; Sugimoto, N.; Simons, C.T. et al., "Does the formation of lipopolysaccharide tolerance require intact vagal innervation of the liver?" AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL 85 1-3 (2000) 111-118-111-118

Dessirier, J.M.; Simons, C.T.; Sudo, M.; Sudo, S. et al., "Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine" JOURNAL OF NEUROPHYSIOLOGY 84 4 (2000) 1851-1862-1851-1862

Carstens, E.; Simons, C.T.; Dessirier, J.M.; Carstens, M.I. et al., "Role of neuronal nicotinic-acetylcholine receptors in the activation of neurons in trigeminal subnucleus caudalis by nicotine delivered to the oral mucosa" EXPERIMENTAL BRAIN RESEARCH 132 3 (2000) 375-383-375-383

Dessirier, J.M.; Simons, C.T.; Carstens, M.I.; O'Mahony, M. et al., "Psychophysical and neurobiological evidence that the oral sensation elicited by carbonated water is of chemogenic origin" CHEMICAL SENSES 25 3 (2000) 277-284-277-284

Simons, C.T.; Dessirier, J.M.; Iodi Carstens, M.; O'Mahony, M. et al., "Erratum: Neurobiological and psychophysical mechanisms underlying the oral sensation produced by carbonated water (Journal of Neuroscience (September 15, 1999) (8134-8144))" Journal of Neuroscience 19 22 (1999) 10191-10191

Sugimoto, N.; Simons, C.T.; Romanovsky, A.A., "Vagotomy does not affect thermal responsiveness to intrabrain prostaglandin E-2 and cholecystokinin octapeptide" BRAIN RESEARCH 844 1-2 (1999) 157-163-157-163

Simons, C.T.; Dessirier, J.M.; Carstens, M.I.; O'Mahony, M. et al., "Neurobiological and psychophysical mechanisms underlying the oral sensation produced by carbonated water" JOURNAL OF NEUROSCIENCE 19 18 (1999) 8134-8144-8134-8144

Jinks, S.; Antognini, J.F.; Carstens, E.; Buzin, V. et al., "Isoflurane can indirectly depress lumbar dorsal horn activity in the goat via action within the brain" BRITISH JOURNAL OF ANAESTHESIA 82 2 (1999) 244-249-244-249

Romanovsky, A.A.; Simons, C.T.; Kulchitsky, V.A., "'Biphasic' fevers often consist of more than two phases" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 275 1 44-1 (1998)

Romanovsky, A.A.; Kulchitsky, V.A.; Simons, C.T.; Sugimoto, N., "Methodology of fever research: Why are polyphasic fevers often thought to be biphasic?" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 275 1 44-1 (1998)

Simons, C.T.; Kulchitsky, V.A.; Sugimoto, N.; Homer, L.D. et al., "Signaling the brain in systemic inflammation: Which vagal branch is involved in fever genesis?" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 275 1 44-1 (1998)

Romanovsky, A.A.; Simons, C.T.; Kulchitsky, V.A.; Sugimoto, N. et al., "Vagus nerve in fever - Recent developments" MOLECULAR MECHANISMS OF FEVER 856 (1998) 298-299-298-299

Romanovsky, A.A.; Simons, C.T.; Szekely, M.; Kulchitsky, V.A., "Febrile irresponsiveness of vagotomized rats to a pyrogenic signal - Non-sensing brain or non-heating body?" THERMOREGULATION 813 (1997) 437-444-437-444

Romanovsky, A.A.; Kulchitsky, V.A.; Simons, C.T.; Sugimoto, N. et al., "Febrile responsiveness of vagotomized rats is suppressed even in the absence of malnutrition" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 273 2 42-2 (1997)

Romanovsky, A.A.; Kulchitsky, V.A.; Akulich, N.V.; Koulchitsky, S.V. et al., "The two phases of biphasic fever - Two different strategies for fighting infection?" THERMOREGULATION 813 (1997) 485-490-485-490

Romanovsky, A.A.; Simons, C.T.; Székely, M.; Kulchitsky, V.A., "The vagus nerve in the thermoregulatory response to systemic inflammation" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 273 1 42-1 (1997)

Romanovsky, A.A.; Kulchitsky, V.A.; Simons, C.T.; Sugimoto, N. et al., "Cold defense mechanisms in vagotomized rats" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 273 2 42-2 (1997)

Romanovsky, A.A.; Kulchitsky, V.A.; Akulich, N.V.; Koulchitsky, S.V. et al., "First and second phases of biphasic fever: two sequential stages of the sickness syndrome?" Am J Physiol 271 1 Pt 2 (1996) R244-R253-R244-R253

Romanovsky, A.A.; Kulchitsky, V.A.; Akulich, N.V.; Koulchitsky, S.V. et al., "First and second phases of biphasic fever: Two sequential stages of the sickness syndrome?" American Journal of Physiology - Regulatory Integrative and Comparative Physiology 271 1 40-1 (1996)

Pennings, J.L.; Bachulis, B.L.; Simons, C.T.; Slazinski, T., "Survival after severe brain injury in the aged" Archives of Surgery 128 (1993) 787-794-787-794

Diamond, S.; Cotten, B.M.; Bahn, T.; Hsiao, Y-H. et al., "Raspberry ketone fails to reduce adiposity beyond decreasing food intake in mice fed a high-fat diet. Food and Function" Food and Function

Simons, C.T., "Ethanol thresholds in water and beer." JOURNAL OF SENSORY STUDIES

Chapters

"Integration of Taste, Smell and Chemesthesis: Clinical Implications" In Sensory Science and Chronic Diseases: Clinical Implications and Disease Management. Edited by Joseph, P.; Duffy, V.. 2021.

"Oral Chemesthesis and Taste" In The Senses: A Comprehensive Reference, second edition. Edited by Meyerhof, W.. 2020.

"Overview of Functional Foods" In Functional Foods and Beverages: In vitro Assessment of Nutritional, Sensory and Safety Properties. 2018.

"Chapter 8. Chemesthesis: Tingling and Numbing" In Chemesthesis: Chemical Touch in Food and Eating. 2016.

"Chapter 50. Trigeminal Chemesthesis" In Handbook of Olfaction and Gustation 3rd Edition. Edited by Doty, R.; Commeto-Muniz, J-E.. 2015.

"Multimodal Interactions: Thermal-Chemical" In Encyclopedia of Perception. Edited by E.B. Goldstein. 2009.

"The “bitter-sweet” truth of artificial sweetener" In Sweetness and Sweeteners: Biology, Chemistry and Psychophysics; American Chemical Society Symposium Series 979. 2008.

"Oral trigeminal sensitivity and taste" In A Comprehensive Reference. Vol 4. Olfaction and Taste. Edited by S. Firestein and G. K. Beauchamp. 2008.

"Activation of neurons in trigeminal subnucleus caudalis (Vc) by irritant chemical stimulation: extracellular single-unit recording and c-fos immunohistochemical methods" In Methods and Frontiers in Chemosensory Research. Edited by S.A. Simon and M.A.L. Nicolelis. 2002.

"The brown fat in the thermoregulatory response of vagotomized rats to lipopolysaccharide" In Temperature Control in Health and Disease. Edited by Gourine, V.N.; Nichelmann, M.; Kulchitsky, V.A.; Patukhov, Y.F.. 1997.

Conferences

Breen, S.P.; Etter, N.M.; Simons, C.T.; Hayes, J.E., "Oral Pressure Point Sensitivity, but not Roughness Sensitivity, is Related to Particle Size Perception in Chocolate" 2018.

Pierce-Feldmeyer, A.M.; Simons, C.T., "The Effect of Orthonasal and Retronasal Odorant Delivery on Multitasking Stress" 2018.

Simons, C.T., "Oral Tactile Sensitivity and Its Role in Texture Perception" 2018.

Pierce, A.M.; Simons, C.T., "Olfactory Adaptation is Dependent on Route of Delivery" 2018.

Liu, E.; Corrigan, J.J.; Lewis, K.; Al-Saffar, H. et al., "Value of fever versus hypothermia in severe sepsis" Federation of American Societies for Experimental Biology 2013.

Klein, A.H.; Sawyer, C.M.; Ivanov, M.A.; Cheung, S. et al., "Tingle sensation by a sanshool derivative and its effects on primary sensory neurons" Chemical Senses 2011.

Simons, C.T.; Albin, K., "Understanding the Relationship Between Saltiness and Umami" 2009.

Slack, J.P.; McCluskey, T.S.; Simons, C.T.; Fushan, A. et al., "Functional Analysis of Naturally Occurring Human Sweet Receptor Variants" 2008.

Simons, C.T.; Fushan, A.; Manichaikul, A.; Drayna, D. et al., "AGFD 205-Genetic influences on sensory perception and its implication to diet" 2008.

Simons, C.T.; Boucher, Y.; Albin, K.; Carstens, M.I. et al., "Nicotine suppression of taste and gustatory responses of NTS neurons" 2006.

Simons, C.T.; Webb, L.; Luzuriaga, D.A.; Burland, M., "Route of administration alters olfactory perception" 2006.

Carstens, E.; Carstens, M.I.; Dessirier, J.M.; O'Mahony, M. et al., "It hurts so good: oral irritation by spices and carbonated drinks and the underlying neural mechanisms" Food Quality and Preference 2002.

Szekely, M.; Balasko, M.; Kulchitsky, V.A.; Simons, C.T. et al., "Multiple neural mechanisms of fever" Autonomic Neuroscience-Basic and Clinical 2000.

Ivanov,A,I; Kulchitsky,V,A; Sugimoto,N; Simons,C,T; Romanovsky,A,A, "Does the formation of lipopolysaccharide tolerance require intact vagal innervation of the liver?" Symposium on Fever - The Role of the Vagus Nerve held at the Experimental Biology 2000 Annual Meeting 2000.

Simons, C.T.; Dessirier, J.M.; Carstens, M.I.; O'Mahony, M. et al., "The tingling sensation of carbonated drinks is mediated by a carbonic anhydrase-dependent excitation of trigeminal nociceptive neurons" Proceedings of the 9th World Congress on Pain 2000.

Romanovsky, A.A.; Simons, C.T.; Kulchitsky, V.A.; Sugimoto, N. et al., "Vagus nerve in fever - Recent developments" Conference on Molecular Mechanisms of Fever 1998.

Kulchitsky, V.A.; Simons, C.T.; Sugimoto, N.; Szekely, M. et al., "Suppression of fever in vagotomized rats: Is it due to malnutrition?" 1997.

Romanovsky, A.A.; Kulchitsky, V.A.; Simons, C.T.; Sugimoto, N. et al., "Febrile irresponsiveness of vagotomized rats: Is it due to thermoeffector incompetence?" 1997.

Simons, C.T.; Kulchitsky, V.A.; Szekely, M.; Romanovsky, A.A., "Lipopolysaccharide (LPS) fever and hypothermia in vagotomized rats." 1997.

Sugimoto, N.; Simons, C.T.; Szekely, M.; Romanovsky, A.A., "Prostaglandin E(2) (PGE(2)) hyperthermia in vagotomized rats." 1997.

Romanovsky, A.A.; Simons, C.T.; Szekely, M.; Kulchitsky, V.A., "Febrile irresponsiveness of vagotomized rats to a pyrogenic signal - Non-sensing brain or non-heating body?" THERMOREGULATION 1997.

Sugimoto, N.; Romanovsky, A.A.; Simons, C.T.; Szekely, M., "Hyperthermic response to central injection of prostaglandin E2 in vagotomized rats" Proceedings from the 1997 Symposium on Thermal Physiology 1997.

Szekely, M.; Simons, C.T.; Kulchitsky, V.A.; Romanovksy, A.A., "The abdominal vagus: its presumed role in fever and in non-febrile temperature regulation" Proceedings from the 1997 Symposium on Thermal Physiology 1997.

Romanovsky, A.A.; Kulchitsky, V.A.; Akulich, N.V.; Koulchitsky, S.V. et al., "The two phases of biphasic fever - Two different strategies for fighting infection?" THERMOREGULATION 1997.

Kulchitsky, V.A.; Akulich, N.V.; Koulchitsky, S.V.; Simons, C.T. et al., "Nociception in systemic inflammatory response: Hyper or hypoalgesia?" FASEB Journal 1996.

Kiesow, L.A.; Simons, C.T.; Long, W.B., "Quantitative determination and comparison of ethanol in saliva samples of unknown volumes with blood ethanol levels in human test subjects following ethanol ingestion." 1993.

Kiesow, L.A.; Simons, C.T.; Long, W.B., "QUANTITATIVE-DETERMINATION AND COMPARISON OF ETHANOL IN SALIVA SAMPLES OF UNKNOWN VOLUMES WITH BLOOD ETHANOL LEVELS IN HUMAN TEST SUBJECTS FOLLOWING ETHANOL INGESTION" CONF ON SALIVA AS A DIAGNOSTIC FLUID 1993.

Patents

A confectionary-based screening tool for assessing chemosensory loss in COVID 19 patients. Filed Oct 2020

Process-as-you-go: multiple, moderate in-situ processes to maximize the food quality trajectory and minimize waste. Filed Apr 2020

A Virtual Reality Platform for Sensory and Consumer Product Testing. Filed Mar 2020

FoodSURE or also FoodS.U.R.E. (Food Science Undergraduate Research Experience). Filed Oct 2016

Christopher T. Simons. Use of Immersive Technology in Consumer Sensory and Acceptance Testing. Filed Apr 2014

Simons, CT, Kaiser, JA, Burland MC, Yates, MT. Retronasal Device And Method. 9121836 Filed Mar 2013 and Issued Sep 2015.

Chad Allen HANSEN; Jay Patrick SLACK; Christopher Todd SIMONS. Consumables. Filed Sep 2012 and Issued Sep 2012.

Chad Allen HANSEN; Jay Patrick Slack; Christopher Todd Simons. Consumables. Filed Aug 2012 and Issued Aug 2012.

NICOLE ERNA IRENE BRUNE; JAY PATRICK SLACK; IOANA MARIA UNGUREANU; KIMBERLY GRAY; CHRISTOPHER TODD SIMONS; JENNY ELLEN EVANS PENNIMPEDE. Methods to Identify Modulators. Filed May 2012 and Issued May 2012.

: UNGUREANU IOANA MARIA; BRUNE NICOLE ERNA IRENE; SIMONS CHRISTOPHER TODD; GRAY KIMBERLEY; SLACK JAY PATRICK. 4-(2, 2, 3-TRIMETHYLCYCLOPENTYL) BUTANOIC ACID USED AS AN OFF-NOTE MASKING AGENT IN CONSUMABLES. Filed Oct 2008 and Issued Oct 2008.

BHOWMIK TARUN; SIMONS CHRISTOPHER TODD; MYAKA STEFKA IVANOVA. FERMENTED INGREDIENT. Filed Oct 2008 and Issued Oct 2008.

Zhonghua Jia; Xiaogen Yang; Chad Allen Hansen; Charles Benjamin Naman; Christopher Todd Simons; Jay Patrick Slack; Kimberley Gray. Consumables. Filed Jun 2008 and Issued Jun 2008.

Ioana Maria Ungureanu; Nicole Erna Irene Brune; Jay Patrick Slack; Kimberley Gray; Christopher Todd Simons; Jenny Ellen Evans Pennimpede. OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS. Filed Mar 2008 and Issued Mar 2008.

Jay Patrick Slack; Christopher Todd Simons; Chad Allen Hansen. METHOD RELATING TO SWEETNESS ENHANCEMENT. Filed Apr 2007 and Issued Jan 2007.

Presentations

"Sensory Evaluation in the 21st Century: New Approaches to Old Issues." In Archer Daniels Midland Global Nutrition Group. 2020.

"Towards a Better Understanding of Food Perception and Liking.." In Mane Inc. Global Strategy Meeting. 2019.

"Exploring oral tactile sensitivity." In Pangborn Sensory Science Symposium. 2019.

"The Person in the Place: Exploring the Eating Experience." In Pangborn Sensory Science Symposium. 2019.

"Manipulating environmental context to explore consumer behaviors (Flash presentation)." In Pangborn Sensory Science Symposium. 2019.

"Impact of Context and Priming on Product Testing." In Institute of Food Technologists. 2019.

"Consumer insights: New approaches to old issues." In Global Statistics Network: Sensometrics and Consumometrics. 2019.

"Contextualizing Context: The Use of Immersive Technologies in Consumer Sensory Testing." In Flavor Summit: Industry Perspectives. 2019.

"“Date Labels & Discard: Results from Consumer Experiments,”." In Penn State University. 2018.

"Wine-ing about context—Does environment matter? Wine perception and liking in traditional booths compared to a virtual and actual wine bar." In Symposium: Context Throwdown. 2018.

"Using immersive technologies to provide context during consumer acceptance testing." In Society for Sensory Professionals. 2018.

"“Discard Intentions are Lower for Milk Presented in Containers without Date Labels,”." In AAEA Annual Meetings. 2018.

"Sensory properties of food and implications for food choice." In "The Future of Taste and Health -- Converging Areas of Science to Promote Healthy Dietary Patterns. 2018.

"Oral tactile sensitivity and its role in texture perception." In Association of Chemoreception Sciences. 2018.

"Using immersive technologies to provide context during consumer acceptance testing." In 14th Sensometric Society Conference. 2018.

"Finding harmony in sensory and physiological data: A symphony of success." In Procter & Gamble. International Technical Research Forum: Symphony.. 2017.

"Consumer Immersion: Investigating the Impact of Context on Consumer Liking and Behavior." In Nestle Technical Center. 2017.

"Mechanisms underpinning oral texture perception." In Pangborn Sensory Science Symposium. 2017.

"Consumer Testing Using Immersive Technologies." In Pangborn Sensory Science Symposium. 2017.

"Towards a Better Understanding of Food Perception and Liking." In The Kellogg Company. 2017.

"The Use of Immersive Technology in Consumer Sensory Testing." In 4th Flavor, Fragrance & Perception Conference. 2017.

"Elucidating the absorption and metabolism of linalool to understand its potential health benefits." In Institute of Food Technologists Annual Meeting and Food Expo. 2017.

"Creation of an Interdisciplinary Sugar Reduction Working Group." In Association of Chemoreception Sciences. 2017.

"Multidisciplinary Research: Towards a Better Understanding of Flavor Perception and Liking." In Association Chemoreception Sciences. 2017.

"Vexed by Context? Using Immersive Technologies to Guide Product Development." In Ohio Food Indusrty Summit 2017; Center for Innovative Food Technology. 2017.

"The role of ecological validity, context and engagement in food perception and liking." In Perryam & Kroll National Strategy Meeting. 2017.

"Sensory Evaluation in the 21st Century: New Approaches to Old Issues." In The Steam Factory, The Ohio State University. 2016.

"Sensory Research Program." In Flavor Research and Education Center. 2016.

"Contextualizing Context: Investigating the Role of Environmental Cues on Product Acceptance Using Immersive Technologies.." In Society for Sensory Professionals. 2016.

"The role of ecological validity, context and engagement in food perception and liking." In Coca-Cola Corp. Global Strategy Meeting. 2016.

"Sensory Myth Busters: Sensory Booths and Colored Lights...Fact or Fiction?." In Institute of Food Technologists. 2016.

"Sensory as a science: Where are we going?." In McCormick Scientific Technical Advisory Panel. 2016.

"The Role of Flavor in the Ever Changing Nutrition Environment." In American Frozen Food Institute Continuing Education Webinar. 2016.

"The Interface of Taste and Sensory Science." In Kerry Group Nutrition Symposium. 2016.

"Consumer Perceptions and Preferences Impacting Food Choices." In Kerry Group Nutrition Symposium. 2016.

"Perplexed by context: The use of immersive technologies to study the impact of extrinsic contextual cues on the perception and liking of foods." In Pangborn Sensory Science Symposium. 2015.

"You’re Taking it out of Context: Using Immersive Technologies to Improve Traditional Consumer Sensory Testing." In Korean Society of Food Science and Technology Annual Meeting. 2015.

"Open Innovation: benefitting chemoreception science through collaborative research." In Association of Chemoreception Sciences. 2014.

"Sensory Evaluation in the 21st Century: New Approaches to Old Questions." In Mid-America Food Processors Association. 2014.

"Sensory Research at The Ohio State University." In Givaudan Flavors Corp. Consultants Day. 2014.

"Exploring the Mysteries of Flavor, Aroma and Apptite." In Northeast Ohio Agribusiness Forum. 2013.

"Chemesthesis: Psychophysics and Neurobiological Underpinnings." In Procter & Gamble: Skin Care Clinical Research Forum. 2013.

"Application of Chemosensory Science to Industry Needs: Sugar Replacement, Salt Reduction and Aromatherapy.." In Association of Chemoreception Science.

"Chemosensory Model Systems." In Association of Chemoreception Sciences.

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